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pentobarbital will reduce the level or effect of trazodone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.pentobarbital will lessen the level or impact of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.pentobarbital will lessen the level or effect of abiraterone by influencing